Have few or no children Have a history of infertilityirregular periodsor abnormal cells in the endometrium called endometrial hyperplasia Have a family history of endometrial, colorectal, or breast cancer Women taking the drug tamoxifen to treat or prevent breast cancer have a slightly higher risk of endometrial cancer.
The endometrium is the tissue lining the inner cavity of the uterus or womb. The upper part of the uterus is called the corpus; the lower, narrower part of the uterus is called the cervix.
The cervix is the Uterine cancer between the uterus and the vagina. The outer layer of the uterus is called the myometrium. The myometrium is thick and composed of strong muscles. These muscles contract during labor to push out the baby. The endometrium is soft and spongy.
Each month, the endometrium is sloughed and thereby changed as part of the menstrual cycle. Early Uterine cancer the cycle, the ovaries secrete a hormone called estrogen that causes the endometrium to thicken. In the middle of the cycle, the ovaries start secreting another hormone called progesterone.
Progesterone prepares the innermost layer of the endometrium to support an embryo should conception pregnancy occur. If conception does not occur, the hormone levels decrease dramatically.
The innermost layer of the endometrium is then shed as menstrual fluid. This leads to the cyclical nature of the menstrual cycle. Endometrial cancer occurs when cells of the endometrium undergo a degenerative change or malignant transformation and begin to grow and multiply Uterine cancer the control mechanisms that normally limit their growth.
As the cells grow and multiply, they form a mass called a cancer or malignant tumor. Cancer is dangerous because it overwhelms healthy cells by taking their space and the oxygen and nutrients they need to survive and function.
It can also spread, or metastasizeto other organs or tissues where it can also do damage. Not all tumors are cancerous.
Benign tumors of the uterus can grow in the uterus but do not spread elsewhere in the body. Cancerous tumors are called malignant, meaning they can look very abnormal, can grow rapidly and erratically, and spread to other tissues and organs.
Cancerous tumors may encroach on and invade neighboring organs or lymph nodesor they may enter the bloodstream or lymph fluid passages and can spread to the bones or distant organs, such as the lungs.
This process is called metastasis. Metastatic tumors are the most aggressive and serious complications of all cancers. Two main types of endometrial cancers exist.
Nearly all endometrial cancers are endometrial adenocarcinomas, meaning they originate from glandular secreting tissue. The other type of endometrial cancer, uterine sarcomas, originates in the connective tissue or muscle of the uterus.
A subtype of endometrial adenocarcinomas, adenosquamous carcinomaincludes squamous cells that is, the type of cells found on the outer surfaces such as the skin or the outermost layer of cells on the uterine cervix.
Other subtypes of endometrial adenocarcinomas are papillary serous adenocarcinomas and clear cell carcinomas. Because they are much more common than uterine sarcomas, endometrial adenocarcinomas are the focus of this article.
In developed countries, uterine cancer is the most common cancer of the female genital tract. In the United States, uterine cancer is the fourth most common cancer in women.
Uterine cancer occurs in women of reproductive age and older. About one-quarter of cases occur before menopausebut the disease is most often diagnosed in women in their 50s or 60s. The exact cause of endometrial carcinoma remains unknown, although several risk factors have been identified.
Possessing one of these risk factors does not mean that a woman will develop endometrial cancer but rather that her risk of developing endometrial cancer is higher than that of another woman without the risk factor. Risk factors for endometrial cancer include the following: Women who are more than 50 pounds over ideal weight have a times greater risk of developing endometrial cancer than women of ideal weight.
Body fat contains an enzyme which converts other hormones to estrogen, and women with excess fat have a higher level of estrogen than women without excess fat.
The higher level of estrogen is believed to increase the risk of endometrial cancer.
Women who have never been pregnant have a two-to three-times higher risk than women who have been pregnant. Women who begin their periods before 12 years of age are at an increased risk. Early puberty increases the number of years that the endometrium is exposed to estrogen.
Women who go through menopause after 52 years of age are at a higher risk of developing endometrial cancer than women who go through menopause earlier in life. Like early puberty, late menopause increases the number of years that the endometrium is exposed to estrogen.The uterus, or womb, is the place where a baby grows when a women is leslutinsduphoenix.com are different types of uterine cancer.
The most common type starts in the endometrium, the lining of the uterus. This type is also called endometrial cancer. Apr 26, · Endometrial cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium.
The endometrium is the lining of the uterus, a hollow, muscular organ in a woman’s leslutinsduphoenix.com uterus is where a fetus grows. In most nonpregnant women, the uterus is about 3 inches long.
Endometrial cancer is a type of cancer that begins in the uterus. The uterus is the hollow, pear-shaped pelvic organ in women where fetal development occurs. Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus.
Endometrial cancer is sometimes called. Uterine cancer resulted in about 58, deaths in up from 45, in Uterine cancer is the fourth most common cancer in women in the UK (around 8, women were diagnosed with the disease in ), and it is the tenth most common cause of cancer death in women (around 2, people died in ).
Uterine cancer may cause vaginal discharge or bleeding that is not normal for you. Bleeding may be abnormal because of how heavy it is or when it happens, such as after you have gone through menopause, between periods, or any other bleeding that is longer or heavier than is normal for you.
Uterine Cancer Symptoms: Vaginal Bleeding. Normal vaginal bleeding is the periodic blood that flows as a discharge from the woman's uterus.
Normal vaginal bleeding is also called menorrhea.